The goal of the AI4HyDrop project is to develop a comprehensive and dynamic framework based on Artificial Intelligence (AI) to ensure the safe operation of drones in restricted and urban areas. This project aims to address various research questions and objectives, including assessing and quantifying the level of safety for U-space operations, defining a safety framework for strategic and tactical operations, determining the acceptable level of automation and AI integration, optimizing airspace usage, and establishing a rational flight approval process. By leveraging AI techniques, the project seeks to pave the way for automated air traffic management, enabling the efficient and secure integration of drones into airspace while considering potential risks, societal impacts, and environmental concerns.